ϸѧ γ̰̽ 11

ڿĿѧ½ڻ⣩
ʮһ ϸڼ

ڿ͡

ۿ

ڿʱ

12 ܵ1-3

ѧĿҪ

  1. ˽ϸڼõϸͬ
  2. ʶ˿Ѻͼѵص
  3. ϸڸʱCDKCyclinϸڵĵ
  4. ϸڼϸڵؼDNA޸

ѧݣݡص㡢ѵ㣩

һ
һʲôϸ          ϸʱIJⶨ
ϸͬ
ڶ ˿
һϸѵ          ˿

һ                      Ḵ
Ľ ϸڵ
һо           CDK           CKI           ġCyclin
塢DNAƵҽһ      MCDKļ
ߡϸڼ           ˡӶϸֳӰ
ص

  1. ˿Ѻͼѵͬ
  2. ϸڸʱCDKCyclinϸڵĵ
  3. ϸڼϸڵĵ

ѵ
    ϸڸʱCDKCyclinϸڵĵأDNAƵġִա˵

ѧֶ뷽
    ͨϸ˿ѡѹ̵ĽڣʹѧϸѸԵص㣬ӶȽϳϸѵͬ㣻ͨѹḴṹȾɫ彻ãʹѧȷֳȷĶԣǿӦ仯ͨMPFķּõĽڣʹѧȷϸڸʱиԵϸڵ׿ϸؽУԿϸתڵ׽ص㽲ڡ
ýѧPPT϶Videoѧ

˼⡢⡢ҵ
1. ʲôϸ? ϸڸʱҪ仯ʲô?
2. ԱȽ˿ѵͬ㡣
3. ϸͨʲôƽȾɫе? кѧ?
4. ˵ϸѺȾɫƶ˶ơ
5. ϸЩҪ,ʲô?
6. ˵CyclinCDKϸִеڹܵ?

οϣο顢׵ȣ

  1. к͡ϲСТϸѧ3棩ߵȽ磬2007
  2. Lodish H et al, Molecular Cell Biology. 5th ed(2004), W. H. Freeman and Company, New York
  3. A1berts B et alEssential Cell Biology. 2nd ed2003, Garland Inc publishing Inc., New York and London
  4. Karp G, Cell and Molecular Biologyconcepts and experiments. 3rd ED. 2006, John WileySons Inc, New York
  5. Donaldson A, Blow JJ. The regulation origin activation[J] Curr Opin in Gene Dev, 1999, 9:62-68.
  6. Princes J. Cyclins and cyclin-dependent kinase: a biochemical view[J]. Biochem J. 1995, 308:697-711.
  7. Elledge SJ. Mitotic arrest: Mad2 provents sleepy from waking up the APC[J]. Science, 1998, 279:999-1000.
 
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